Charles Hoskinson is the CEO and Founder of Input Output Global (IOHK), the company behind the Cardano blockchain, a proof-of-stake platform hosting the ADA cryptocurrency. A mathematician by training, Hoskinson co-founded Ethereum in 2013. 
He launched IOHK with Jeremy Wood in 2015, raising $62 million in a 2017 ICO for Cardano, initially targeting the Japanese market before global expansion. Hoskinson advocates for decentralized governance, as seen in Cardano’s 2024 Voltaire framework and 2025 Wyoming Integrity PAC to challenge state stablecoin policies. 
His ventures extend to longevity science, with a $100 million investment in the Hoskinson Health & Wellness Clinic in Wyoming, and quirky pursuits like glow-in-the-dark botany and a 2023 Papua New Guinea expedition for extraterrestrial objects. With a net worth estimated at $1.2 billion, he owns an 11,000-acre Wyoming ranch and remains a vocal critic of centralized control in crypto.

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Cardano - cardano.org/

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00:00 Introduction & Guest Welcome
01:11 Charles Hoskinson’s Background
03:37 The Future of Cryptocurrencies & Stablecoins
07:20 Blockchain Interoperability & Innovation
20:33 Bioluminescence & Synthetic Biology
36:22 Quantum Computing & Cryptography
48:58 Cryptography, Security & National Implications
54:15 Personal Journey: Hawaii to Colorado
01:02:42 Discovering Math, Politics & Crypto Philosophy
01:28:47 Blockchain Voting & Governance
01:50:19 Digital Identity & Trust Systems
02:02:36 Bitcoin in El Salvador & Global Finance
02:14:27 Economic Blocks, Tensions & Debt Crisis
02:21:26 Global Governance & Tech Disruption
02:33:55 Ethereum’s Origins & Founding Issues
02:52:16 Alien Research & Technology Speculation
03:06:06 Consciousness, Psychedelics & Self
03:40:10 Math, Reality & the Afterlife
03:53:43 Dire Wolf Project & Synthetic Biology
04:16:08 Tribal Rites & Pushing Human Limits
04:27:28 Medical Innovation & Regenerative Tech
04:53:19 Journaling & Personal Knowledge
04:58:20 Final Thoughts